Huygens has a SPIM optical option available for excellent deconvolution for more than a year but specific fusion still needed to be done manually. Now we have released also the SPIM/ LightSheet Fusion & Deconvolution Wizard in the new 17.04 version of Huygens

Combined with the SPIM/LightSheet optical Option we offer a wizard-based solution in which deconvolution, scattering correction, and restoration (fusion) of various types of multiview SPIM/Light sheet data is combined to facilitate efficient use of computational resources.

Accurate registration and fusion of multi-directional and rotational views of 3D times series is fully automated, and specific optical parameters for SPIM/Light Sheet images - like sheet direction, NA, fill factor, and focus and lateral offset - ensure optimal deconvolution results. Additional scatter models are available for correcting apparent Rayleigh scattering.

You can find the 17.04 release on the Huygens Download page and you can request a test license after starting Huygens Professional for instance.