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Huygens Widefield Deconvolution Software

Increase signal, contrast and resolution with the most reliable algorithms available


RAW Widefield
Huygens Deconvolved
One of the main issues with widefield imaging is out-of-focus blur, which typically hinders 3D imaging, and clear object recognition and segmentation. Luckily, Huygens true deconvolution is able to use this fluorescence to increase image resolution and specific object signal. Also brightfield images greatly benefit from the Huygens Widefield & Brightfield Microscope deconvolution option.

Image description:
smFISH in Drosophila Muscle. Composition of megaRNPs: Pak, Par6, and Cask mRNAs. Nuclei are stained with antilamin antibody (blue). Published in: https://pubmed.ncbi.nlm.nih.gov/32158910/. Image kindly provided by Dr. Akiko Noma, Dr. Carlas Smith & Dr. David Grunwald RNA Therapeutic Institute (RTI), University of Massachusetts Medical School, USA.

Depth dependent PSF

Optimal results with large image stacks. Learn more.

Most advanced algorithms

Huygens uses the most sophisticated Maximum Likelihood Estimation algorithms.

All Microscope Brands

All brands of Widefield & Brightfield Microscopes are supported, as well as many File Formats.


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Testimonials

"Our images are improved amazingly by the Huygens software. That's why we decided to buy the wide-field microscope deconvolution option, and we are very happy with it! Now we are thinking of buying the PSF distill option as well."
MSc. Di Zi, Leiden Institute of Advanced Computer Science (LIACS), Leiden University, The Netherlands.

"So far Huygens seems to surpass our other products at least for deconvolution and also surface rendering, and most of all, the technical support that you have provided is truly tremendous."
Huong Ha, Neuroscience Program, Stanford University, USA.


Raw Widefield
Huygens Deconvolved
Stained structures (kinetochore complex) involved in cell division, Image kindly provided by Dr. Livio Kleij (facility) and Martijn Vroomans. Medical Oncology, UMC Utrecht, The Netherlands.



See more: Images in the field of Genetics Biology

Raw Widefield
Huygens Deconvolved
smFISH in Drosophila Muscle. Composition of megaRNPs: Pak, Par6, and Cask mRNAs. Nuclei are stained with antilamin antibody (blue). Published in: https://pubmed.ncbi.nlm.nih.gov/32158910/. Image kindly provided by Dr. Akiko Noma, Dr. Carlas Smith & Dr. David Grunwald RNA Therapeutic Institute (RTI), University of Massachusetts Medical School, USA.

See more: Images in the field of Cell Biology


Available for Huygens Essential, Professional and Core

The Huygens Widefied & Brightfield optical option supports all brands of widefield & brightfield microscopes. The option can be tested with a free test license. The product is commercially available as a licensed option for Huygens Essential, Professional and Core.

Why wait? Try out this option by downloading Huygens and request a test license, or receive pricing information.

Pricing Info Request Trial