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Webinar June 4th. STEDYCON & HUYGENS: super-resolution scaled up - featuring Huygens Stitcher

Thursday 28 of May, 2020
STEDYCON & HUYGENS: super-resolution scaled up - featuring Huygens Stitcher
Date : June 4, 2020
Starting time: 3:30 PM CEST
End time: 4:30 PM CEST

Sign up now for this webinar in collaboration with Abberior Instruments: STEDYCON & HUYGENS: super-resolution scaled up - featuring Huygens Stitcher.

For more information on the Huygens Stitcher for all your microscopy data types, please visit this webpage

You can register here for the Abberior-Huygens webinar.

Huygens facilitates research on Corona/RNA viruses already for many years

Friday 17 of April, 2020
We are very proud that we could contributed with HUYGENS to many research articles on Corona related research.
Below is a selection of publications and preprints that have been made available online:


González-Domínguez I, Puente-Massaguer E, Cervera L, Gòdia F. (2020). Quality Assessment of Virus-Like Particles at Single Particle Level: A Comparative Study.
Viruses 2020, 12(2), 223
Huygens was used for deconvolving Leica SP8 confocal data.

González-Domínguez I, Puente-Massaguer E, Cervera L, Gòdia F. (2020). Quantification of the HIV‐1 virus‐like particle production process by super‐resolution imaging: from VLP budding to nanoparticle analysis.
Biotechnology and Bioengineering. April 2020
Huygens was used for deconvolving confocal data.

Aoyama-Ishiwatari S, Okazaki T, Iemura S-i, Natsume T, Okada Y, Gotoh Y. (2020). NUDT21 links mitochondrial IPS-1 to RLR-containing stress granules and 3 activates host antiviral defense.
bioRxiv, preprint April 2020
Huygens was used for deconvolution and 3D object counting.

Lingemann M, McCarty T, Liu X, Buchholz UJ, Surman S, Martin SE, Collins PL, Munir S (2019).
The alpha-1 subunit of the Na+,K+-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells.
Plos Pathogens, 05 Aug 2019
Huygens was used for deconvolution

Matczuk,AK, Chodaczek G, Ugorski M. (2019). Production of Recombinant EAV with Tagged Structural Protein Gp3 to Study Artervirus Minor Protein Localization in Infected Cells
https://europepmc.org/article/MED/31404947#free-full-text|Viruses. 2019 Aug; 11(8): 735.]
Huygens was used for deconvolution

Lingemann M, McCarty T, Liu X, Buchholz UJ, Surman S, Martin SE, Collins PL, Munir S (2019).
The alpha-1 subunit of the Na+,K+-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells.
Plos Pathogens, 05 Aug 2019
Huygens was used for deconvolution

Karelehto E, Cristella C, Yu X, Sridhar A, Hulsdouw R, de Haan K, van Eijk H, Koekkoek S, Pajkrt D, de Jong MD, Wolthers KC (2018). Polarized Entry of Human Parechoviruses in the Airway Epithelium
Front Cell Infect Microbiol. 2018; 8: 294.
Huygens was used for deconvolution of confocal images

Yue Y, Nabar NR, Shi C-S, Kamenyeva O, Xiao X, Hwang I-Y, Wang M, Kehrl JH. (2018). SARS-Coronavirus Open Reading Frame-3a drives multimodal necrotic cell death.
Cell Death Dis. 2018 Sep; 9(9): 904.
Huygens was used for deconvolution of confocal images

Milewska A, Nowak P, Owczarek K, Szczepanski A, Zarebski M, Hoang A, Berniak K, Wojarski J, Zeglen S, Baster Z, Rajfur Z, Pyrc K (2018). Entry of Human Coronavirus NL63 into the Cell..
Journal of Virology, 17 Jan 2018, 92(3)
Huygens was used for deconvolution of both Zeiss and Leica confocal images


....and more

Nature Protocols: "guidance for quantitative confocal microscopy" acknowledges Huygens Software

Friday 03 of April, 2020
We like to congratulate James Jonkman, Claire M. Brown, Graham D. Wright, Kurt Anderson and Alison J. North with the publication of their review paper in Nature Protocols on quantitative confocal microscopy. A huge piece of work and a great contribution to the field of microscopy.

See here: https://www.nature.com/articles/s41596-020-0313-9

SVI is of course very pleased that Huygens is well acknowledged as the software that uses powerful algorithms and has deconvolution specifically designed for many different kinds of microscopes (including CLSM, Spinning Disk, multi-photon, Airyscan, STED, etc.).

The article correctly states that manually setting the SNR and background parameters for deconvolution needs some experience. The benefit of this: it makes Huygens unique in its handling of both low and high signal image data from all types of microcopes.

Huygens new options such as Deconvolution Express and Batch Express allow fully automated deconvolution of all types of microscopy images.

We have an upcoming WEBINAR on Batch Express on April 7th: register here.

High quality winning image of Huygens 2019 Image Contest recognized by the Australian Microscopy and Microanalysis Society

Wednesday 01 of April, 2020
The image of Howard Vindin (Weiss Lab, Charles Perkins Centre, The University of Sydney), which won the 1st prize in the Huygens Image Contest 2019, has been selected for the cover of the March issue of The Australian Microscopy and Microanalysis Society (AMMS).

You can view all the Huygens Image Contest prize winners here: https://svi.nl/ImageContestWinners

To download the March issue of the Australian Microscopy and Microanalysis Society (AMMS), you need to be a member: https://microscopy.org.au/login/

Huygens Localizer published in Microscopy Today (this March issue + cover)

Thursday 19 of March, 2020
With the help of many research groups and imaging facilities worldwide, we have published Huygens Localizer in this Microscopy Today March issue. This article summarizes all the advantages of using Huygens Localizer for 2D and 3D SMLM (PALM, STORM, GSDIM, PAINT) analysis, and compares its performance, accuracy and precision with the most commonly used package ThunderSTORM.

This article could not have been made without the help of many research groups that contributed with images and with suggestions during the development of Huygens Localizer. Special thanks to groups at the University of Helsinki, the ALMF - EMBL Heidelberg, the Goethe University Frankfurt, the Erasmus Medical Center Rotterdam, and the University of Calgary (see also the "Acknowledgements" paragraph).

View the Microscopy Today March2020 issue or download the PDF online

Huygens support continues 100%

Sunday 15 of March, 2020
As everybody the corona crisis shocked our team and we hope for the recovery of those affected by Covid19.

We want to assure our customers and relations that the Huygens team stays ready to support you fully.
In case you need to work from home ask a temporary Huygens for Home license via https://svi.nl/LicenseRequest or https://svi.nl/LicenseRequest-chinees.
In case you have support or product questions contact sales at svi.nl or support at svi.nl

Get your 'Huygens@Home' in case of Corona crisis measures at work. CPU and/or GPU computers OK.

Sunday 15 of March, 2020
Are you working from home due to the Corona measures, and do you have limited or no access to your image processing workstation/server at the lab or facility? SVI would like to offer researchers a temporary Huygens license (Huygens@Home) for their personal laptop or PC. Huygens@Home will work on CPU only and CPU and GPU NVidia laptops and PC's.

For all customers outside China, visit Request a license here, and state in the field "Department" your department or lab name also: 'Huygens@Home' .

For our Chinese customers: visit Request a license here, and state in the field "Department" your department or lab name also: 'Huygens@Home' .

100 days of free testing Huygens Localizer for SMLM analysis

Tuesday 18 of February, 2020
We like offer you the option to try Huygens Localizer for analyzing 2D and 3D (astigmatic) SMLM image data for 100 days.
We initially supply you with a 10 day test period, which can be easily extended with another 90 days if you fill out a survey.
This survey will take about 5 minutes to complete and will provide us with very valuable information on how we can further improve

If you do not have a login for our website, you can register here, to join this 100 days of testing.

Else, login with your credentials and visit this webpage.



Webinar on image processing via the web interface Huygens Remote Manager

Tuesday 11 of February, 2020
Join us with this webinar on the new release of Huygens Remote Manager version 3.7.
HRM can be used by multiple users simultaneously and is ideally suited for batch processing, including deconvolution, chromatic aberration correction, time stabillization and colocalization analysis.

By using HRM via your web-browser, you can submit image processing jobs anywhere and at anytime with your computer.
HRM uses multi-core CPUs and GPUs, ensuring that computational resources are used optimally.

You can register here for one of the webinar sessions.

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Upcoming Events

Wed 30 of Sep, 2020 00:00 CEST
SVI Huygens imaging Course in 2021