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News

Huygens CMLE deconvolution on GPU, now available for testing!

Wednesday 15 of July, 2015
Increase your computing performance by using the power of the graphics processing unit (GPU). GPU accelerated Huygens deconvolution is now available as a test version of the Huygens software. Huygens GPU accelerated deconvolution is available free of charge for CUDA-enabled NVidia graphics cards containing max 2Gb of video RAM and max 512 CUDA cores/shading units. For graphics cards containing more RAM and CUDA cores an additional option is required in your Huygens license. If you have an NVidia graphics card and would like to receive a test license, please contact license at svi.nl. Currently GPU accelerated Huygens deconvolution is available for Windows and Linux (Ubuntu/Debian distribution) and for deconvolution of images with the CMLE algorithm. Instructions for testing the Huygens GPU deconvolution, can be found here.

Huygens deconvolved image on cover of J. Neuroscience

Monday 06 of July, 2015
Researchers at the Queensland Brain Institute published a great image on the cover on The Journal of Neuroscience that was deconvolved with Huygens. More details on this image can be found via this link.
We want to thank Faith Brennan and Luke Hammond, who created this image, for allowing us to publish this information.

Deconvolution of Very Large Data Sets with Huygens is published in Imaging & Microscopy

Monday 01 of June, 2015
Scientific Volume Imaging is proud to announce that the article Deconvolution of Very Large Data Sets by A. Ponti, Y. Belyaev, N. Ehrenfeuchter and D. Sevilla Sanchez, has been published in the most recent edition of Imaging & Microscopy Issue 2, 2015.
In this paper the authors describe how the Huygens Remote Manager, which is the open-source and web-based deconvolution scheduler for Huygens Core, can be used to efficiently schedule and process deconvolution jobs for very large datasets with sizes as large as 1 TB, generated by spinning-disk and SPIM microscopes. Because spinning-disk and SPIM systems allow for very fast and large field-of-view 3D imaging, they are often used in studies of Drosophila Embryo development. However, like all optical microscope systems, the images generated by these systems also suffer from noise and blurring, but luckily the images can be efficiently restored with the powerful Huygens deconvolution algorithms.

Article abstract: The Huygens Remote Manager (HRM) is an open-source, multi-user, web-based batch processor for large scale restoration of microscopy images. By enabling mass deconvolution, HRM aims at maximizing the volume of data suitable for segmentation, quantification and analysis. Recent deconvolution runs of large spinning disk and SPIM images show that while these images present a true challenge for current desktop computers, they can be easily processed on a small HRM server automatically.

The complete issue 2, 2015 of Imaging & Microscopy can be found here and the article can be found on page 22-23.

We would like to acknowledge Dr. Livio Kleij (facility) and Dr. Martijn Vromans, Dept of Medical Oncology, UMC Utrecht, The Netherlands for providing the image presented in the article header.

Unique new van Leeuwenhoek (1632-1723) Microscope discovered

Friday 22 of May, 2015
A single objective microscope designed and made by Antony van leeuwenhoek (1632-1723) has recently been discovered in a dollś-house attributes collection in the UK. The Museum Boerhaave has proven that the unique antique microscope was designed and build by van Leeuwenhoek himself by comparing it with the five real 'van Leeuwenhoekjes' as present in its collection.

The Dutch Van Leeuwenhoek is considered to be the "Father of Microbiology" and played a very important role in the early development of the optical microscope.
The recently discovered microscope was part of a collection in the UK for centuries without the owners knowing its historical value. The whole collection was recently purchased by Bert Degenaar on behalf of a Dutch foundation planetarium Zuylenburgh. Alerted by the likeliness to other Van Leeuwenhoek single lens microscopes he requested further investigation.

The microscope will be on display at the Leiden Science Museum until the end of June 2015, fter that it will be transferred to the Planetarium Zuylenburg near Utrecht (NL).

The manager of the Golub collection in Berkeley, Dr. Steve Ruzin was present when the microscope was discoverd to be a real 'Van Leeuwenhoek'.

Nyquist Calculator on SVI website offers STED & 3D STED sampling! SVI Nyquist App for Android

Tuesday 03 of March, 2015
For many years we already have a freely accessible online Nyquist Calculator on our website.

This Nyquist Calculator determines the optimal theoretical sampling density for your microscopic-image acquisition. With the computed sampling density you will make optimal use of the resolution of your microscope and minimize image distortions. Additionally, the Nyquist Calculator can visualize the Point Spread Function (PSF) for various microscope types and parameters in all dimensions.

Since January 2015 we have two versions:



Huygens Image Contest 2014 winners

Monday 22 of December, 2014

Winners Huygens Image Contest 2014


We thank all of our Huygens users for submitting their high quality images and movies to us for the contest. The winning image is from Dr. Imre Gaspar, who won a Google Nexus 9 inch tablet and a 1 year license of Huygens Titan. The image was recorded with a Leica SP8 confocal and deconvolved with the Huygens Remote Manager and Core at the Advanced Light Microscopy Facility of the EMBL Heidelberg, Germany. The second and third prizes were a Huygens Titan license. All winning images are shown here.

Huygens Image Contest 2014 winners

Monday 22 of December, 2014
We thank all of our Huygens users for submitting their high quality images and movies to us for the contest. The winning image is from Dr. Imre Gaspar, who won a Google Nexus 9 inch tablet and a 1 year license of Huygens Titan. The image was recorded with a Leica SP8 confocal and deconvolved with the Huygens Remote Manager and Core at the Advanced Light Microscopy Facility of the EMBL Heidelberg, Germany. The second and third prizes were a Huygens Titan license. All winning images are shown here.

Confocal Leica SP8 and Huygens combined to push the resolution limits

Wednesday 10 of December, 2014
Click on the image for a pdf of this brochure
Click on the image for a pdf of this brochure
Thanks to the continued collaboration between Leica Microsystems and Scientific Volume Imaging, you will find the Huygens software now with Leica Confocal TCS SP8 systems. All Leica SP8 STED systems are already equipped with the Huygens software, so STED users are already familiar with the intuitive image transfer between LAS X and Huygens plus the excellent improvements in image resolution and intensity. The modular TCS SP8 system is a state-of-the-art flexible Confocal system that can be expanded with STED and that is now equipped with Huygens as well.

The Leica - SVI Huygens brochure gives you detailed information how to optimally configure the settings of your TCS SP8 microscope to obtain maximum resolution with Huygens. Are you interested about the Huygens-Leica data exchange option? You can check here if your Leica and Huygens software are compatible for it!

Nobel prize Chemistry 2014 awarded for the development of super-resolved fluorescence microscopy

Wednesday 08 of October, 2014
Ernst Abbe's formula for the diffraction limit, set in stone at a monument in Jena. Source: Wikpedia Creative Commons.
Ernst Abbe's formula for the diffraction limit, set in stone at a monument in Jena. Source: Wikpedia Creative Commons.
Stefan W. Hell, Eric Betzig, and William E. Moerner have been awarded the Nobel prize of Chemistry (2014) for developing microscopy techniques that beat the traditional optical resolution limit. Stimulated Emission Depletion (STED) and singe-molecule microscopy has a huge impact on fluorescence optical microscopy related research, allowing scientist to see more detail of their fluorescent labeled objects (see movie below).

SVI with Hans van der Voort, founder of SVI and co-author on several publications with Stefan Hell, congratulate him, and Eric Betzig and William E. Moerner with this big achievement!



A small selection of amazing Huygens deconvolution results on biological STED data is shown in this STED Gallery

SVI Huygens founded 20 years ago

Thursday 04 of September, 2014
We want to thank first and foremost all our customers for making it possible to celebrate our 20th anniversary.

Started on September 1, 1994 by Hans van der Voort, SVI has grown steadily ever since thanks to an also steadily growing number of very loyal customers.
Their input has always been leading for our innovations and development.

So we want to thank them in particular for making this special event possible.
We'll keep on listening carefully to them while making the best possible imaging and deconvolution software for microscopic data based on our mutual expertise.






Contact Information

Scientific Volume Imaging B.V.

Laapersveld 63
1213 VB Hilversum
The Netherlands


Phone: +31 (0)35 64216 26
Fax: +31 (0)35 683 7971
E-mail: info at svi.nl

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